For PubMed listing click HERE
Berry KJ, Chandran U, Mu F, Deochand DK, Lei T, Pagin M, Nicolis SK, Monaghan-Nichols AP, Rogatsky I, DeFranco DB. Genomic glucocorticoid action in embryonic mouse neural stem cells. (2023) Mol Cell Endrocrinol 1;563:111864
Dacic M, Shibu G, Rogatsky I. Physiological convergence and antagonism between GR and PPARγ in inflammation and Metabolism (2022) Adv Exp Med Biol. 2022;1390:123-141
Mimouna S*, Rollins DA*, Shibu G, Tharmalingam B, Deochand DK, Chen X, Oliver D, Chinenov Y, Rogatsky I. Transcription cofactor GRIP1 differentially affects myeloid cell–driven neuroinflammation and response to IFN-β therapy (2020) J Exp Med 218 (1):e20192386 (* equal contribution)
Yu L , Zhang B, Deochand D, Sacta MA, Coppo M, Shang Y, Guo Z, Zeng X, Rollins DA, Tharmalingam B, Li R, Chinenov Y, Rogatsky I* and Hu X*. Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression (2020) Nat Commun 11, 2286 (*co-corresponding authors)
Sacta MA, Tharmalingam B, Coppo M, Rollins DA, Deochand DK, Benjamin B, Yu L, Zhang B, Hu X, Li R, Chinenov Y, Rogatsky I. Gene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages (2018) Elife. Feb 9;7. pii: e34864
Rollins DA, Kharlyngdoh JB, Coppo M, Tharmalingam B, Mimouna S, Guo Z, Sacta MA, Pufall AM, Fisher RP, Hu X, Chinenov Y and Rogatsky I. Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages (2017) Nature Commun 8:1739
Coppo M., Chinenov Y., Sacta M.A. and Rogatsky I. Transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis (2016) Nature Commun 7:12254
Shang Y., Coppo M., Ning F., Yu L., Kang L., Zhang B., Ju C., Qiao Y., Zhao B., Gessler M., He T., Rogatsky I. and Hu X. The transcriptional repressor Hes1 attenuates inflammation via regulating transcriptional elongation (2016) Nature Immunology 17:930-7
Sacta M.A., Chinenov Y. and Rogatsky I. Glucocorticoid signaling: An update from a genomic perspective (2016) Annu Rev Physiol. 78:155-80
Chinenov Y., Coppo M., Gupte R., Sacta M.A. and Rogatsky I. Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages (2014) BMC Genomics 15:656
Rogatsky I. and Adelman K. Preparing the first responders: Building the inflammatory transcriptome from the ground up (2014) Molecular Cell 54:245-54
Gupte R., Muse G.W., Chinenov Y., Adelman K. and Rogatsky I. Glucocorticoid receptor represses pro-inflammatory genes at distinct steps of the transcription cycle (2013) Proc. Natl. Acad. Sci. USA 110:14616-21
Chinenov Y., Gupte R., Dobrovolna J., Flammer J.R., Liu B., Michelassi F.E. and Rogatsky I. The role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids (2012) Proc. Natl. Acad. Sci. USA 109:11776-81
Dobrovolna J., Chinenov Y., Kennedy M.A., Liu B. and Rogatsky I. Glucocorticoid-dependent phosphorylation of the transcriptional coregulator GRIP1 (2012) Mol. Cell. Biol. 32:730-9
Flammer J.R., Dobrovolna J., Kennedy M.A., Chinenov Y., Glass C.K., Ivashkiv L.B., Rogatsky I. Type I interferon signaling pathway is a target for glucocorticoid inhibition (2010) Mol. Cell. Biol. 30: 4564-74
Adelman K., Kennedy M.A., Nechaev S., Gilchrist D.A., Muse G.W.,Chinenov Y., Rogatsky I. Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling (2009) Proc. Natl. Acad. Sci. USA 106:18207-12
Chinenov Y., Sacta M.A., Cruz A.R., Rogatsky I. GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression (2008) Proc. Natl. Acad. Sci. USA 105: 20185-90
Dacic M, Shibu G, Rogatsky I. Physiological convergence and antagonism between GR and PPARγ in inflammation and Metabolism (2022) Adv Exp Med Biol. 2022;1390:123-141
Mimouna S*, Rollins DA*, Shibu G, Tharmalingam B, Deochand DK, Chen X, Oliver D, Chinenov Y, Rogatsky I. Transcription cofactor GRIP1 differentially affects myeloid cell–driven neuroinflammation and response to IFN-β therapy (2020) J Exp Med 218 (1):e20192386 (* equal contribution)
Yu L , Zhang B, Deochand D, Sacta MA, Coppo M, Shang Y, Guo Z, Zeng X, Rollins DA, Tharmalingam B, Li R, Chinenov Y, Rogatsky I* and Hu X*. Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression (2020) Nat Commun 11, 2286 (*co-corresponding authors)
Sacta MA, Tharmalingam B, Coppo M, Rollins DA, Deochand DK, Benjamin B, Yu L, Zhang B, Hu X, Li R, Chinenov Y, Rogatsky I. Gene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages (2018) Elife. Feb 9;7. pii: e34864
Rollins DA, Kharlyngdoh JB, Coppo M, Tharmalingam B, Mimouna S, Guo Z, Sacta MA, Pufall AM, Fisher RP, Hu X, Chinenov Y and Rogatsky I. Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages (2017) Nature Commun 8:1739
Coppo M., Chinenov Y., Sacta M.A. and Rogatsky I. Transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis (2016) Nature Commun 7:12254
Shang Y., Coppo M., Ning F., Yu L., Kang L., Zhang B., Ju C., Qiao Y., Zhao B., Gessler M., He T., Rogatsky I. and Hu X. The transcriptional repressor Hes1 attenuates inflammation via regulating transcriptional elongation (2016) Nature Immunology 17:930-7
Sacta M.A., Chinenov Y. and Rogatsky I. Glucocorticoid signaling: An update from a genomic perspective (2016) Annu Rev Physiol. 78:155-80
Chinenov Y., Coppo M., Gupte R., Sacta M.A. and Rogatsky I. Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages (2014) BMC Genomics 15:656
Rogatsky I. and Adelman K. Preparing the first responders: Building the inflammatory transcriptome from the ground up (2014) Molecular Cell 54:245-54
Gupte R., Muse G.W., Chinenov Y., Adelman K. and Rogatsky I. Glucocorticoid receptor represses pro-inflammatory genes at distinct steps of the transcription cycle (2013) Proc. Natl. Acad. Sci. USA 110:14616-21
Chinenov Y., Gupte R., Dobrovolna J., Flammer J.R., Liu B., Michelassi F.E. and Rogatsky I. The role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids (2012) Proc. Natl. Acad. Sci. USA 109:11776-81
Dobrovolna J., Chinenov Y., Kennedy M.A., Liu B. and Rogatsky I. Glucocorticoid-dependent phosphorylation of the transcriptional coregulator GRIP1 (2012) Mol. Cell. Biol. 32:730-9
Flammer J.R., Dobrovolna J., Kennedy M.A., Chinenov Y., Glass C.K., Ivashkiv L.B., Rogatsky I. Type I interferon signaling pathway is a target for glucocorticoid inhibition (2010) Mol. Cell. Biol. 30: 4564-74
Adelman K., Kennedy M.A., Nechaev S., Gilchrist D.A., Muse G.W.,Chinenov Y., Rogatsky I. Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling (2009) Proc. Natl. Acad. Sci. USA 106:18207-12
Chinenov Y., Sacta M.A., Cruz A.R., Rogatsky I. GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression (2008) Proc. Natl. Acad. Sci. USA 105: 20185-90
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